Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Nephrology
Volume 2015 (2015), Article ID 235982, 4 pages
http://dx.doi.org/10.1155/2015/235982
Case Report

Rhabdomyolysis and Acute Kidney Injury Requiring Dialysis as a Result of Concomitant Use of Atypical Neuroleptics and Synthetic Cannabinoids

State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA

Received 8 June 2015; Revised 21 September 2015; Accepted 29 September 2015

Academic Editor: Neil Boudville

Copyright © 2015 Aiyu Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. L. Mehta and G. M. Chertow, “Acute renal failure definitions and classification: time for change?” Journal of the American Society of Nephrology, vol. 14, no. 8, pp. 2178–2187, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. X. Bosch, E. Poch, and J. M. Grau, “Rhabdomyolysis and acute kidney injury,” The New England Journal of Medicine, vol. 361, no. 1, pp. 62–72, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. R. Vanholder, M. S. Sever, E. Erek, and N. Lameire, “Rhabdomyolysis,” Journal of the American Society of Nephrology, vol. 11, no. 8, pp. 1553–1561, 2000. View at Google Scholar · View at Scopus
  4. T. Leggett, “A review of the world cannabis situation,” Bulletin on Narcotics, vol. 58, no. 1-2, pp. 1–155, 2006. View at Google Scholar
  5. L. Lindsay and M. L. White, “Herbal marijuana alternatives and bath salts—‘barely legal’ toxic highs,” Clinical Pediatric Emergency Medicine, vol. 13, no. 4, pp. 283–291, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. L. K. Brents and P. L. Prather, “The K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products,” Drug Metabolism Reviews, vol. 46, no. 1, pp. 72–85, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. US Drug Enforcement Administration, “Chemicals used in ‘Spice’ and ‘K2’ type products now under federal control and regulation,” 2011, http://www.dea.gov/pubs/pressrel/pr030111.html.
  8. Centers for Disease Control and Prevention (CDC), “Acute kidney injury associated with synthetic cannabinoid use—multiple states, 2012,” Morbidity and Mortality Weekly Report, vol. 62, no. 6, pp. 93–98, 2013. View at Google Scholar
  9. G. K. Bhanushali, G. Jain, H. Fatima, L. J. Leisch, and D. Thornley-Brown, “AKI associated with synthetic cannabinoids: a case series,” Clinical Journal of the American Society of Nephrology, vol. 8, no. 4, pp. 523–526, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Durand, L. L. Delgado, D. M. de la Parra-Pellot, and D. Nichols-Vinueza, “Psychosis and severe rhabdomyolysis associated with synthetic cannabinoid use,” Clinical Schizophrenia & Related Psychoses, vol. 8, no. 4, pp. 205–208, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. M. C. Mallappallil, R. Mehta, E. Yoshiuchi, G. Briefel, E. Lerma, and M. Salifu, “Parameters used to discontinue dialysis in acute kidney injury recovery: a survey of United States Nephrologists,” Nephron, vol. 130, no. 1, pp. 41–47, 2015. View at Publisher · View at Google Scholar
  12. H. L. Corwin, M. J. Schreiber, and L. S. T. Fang, “Low fractional excretion of sodium. Occurrence with hemoglobinuric- and myoglobinuric-induced acute renal failure,” Archives of Internal Medicine, vol. 144, no. 5, pp. 981–982, 1984. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Aggarwal, N. Guanci, K. Marambage, and J. P. Caplan, “A patient with multiple episodes of rhabdomyolysis induced by different neuroleptics,” Psychosomatics, vol. 55, no. 4, pp. 404–408, 2014. View at Publisher · View at Google Scholar · View at Scopus
  14. M. S. Castaneto, D. A. Gorelick, N. A. Desrosiers, R. L. Hartman, S. Pirard, and M. A. Huestis, “Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications,” Drug and Alcohol Dependence, vol. 144, pp. 12–41, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. C. R. Harris and A. Brown, “Synthetic cannabinoid intoxication: a case series and review,” The Journal of Emergency Medicine, vol. 44, no. 2, pp. 360–366, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Steffens and P. Pacher, “Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies,” British Journal of Pharmacology, vol. 167, no. 2, pp. 313–323, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. B. C. Ginsburg, L. R. McMahon, J. J. Sanchez, and M. A. Javors, “Purity of synthetic cannabinoids sold online for recreational use,” Journal of Analytical Toxicology, vol. 36, no. 1, Article ID bkr018, pp. 66–68, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Cavuoto, A. J. McAinch, G. Hatzinikolas, D. Cameron-Smith, and G. A. Wittert, “Effects of cannabinoid receptors on skeletal muscle oxidative pathways,” Molecular and Cellular Endocrinology, vol. 267, no. 1-2, pp. 63–69, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. W. E. Fantegrossi, J. H. Moran, A. Radominska-Pandya, and P. L. Prather, “Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: mechanism underlying greater toxicity?” Life Sciences, vol. 97, no. 1, pp. 45–54, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. K. Watanabe, S. Yamaori, T. Funahashi, T. Kimura, and I. Yamamoto, “Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes,” Life Sciences, vol. 80, no. 15, pp. 1415–1419, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. K. C. Chimalakonda, K. A. Seely, S. M. Bratton et al., “Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands,” Drug Metabolism and Disposition, vol. 40, no. 11, pp. 2174–2184, 2012. View at Publisher · View at Google Scholar · View at Scopus