Homozygosity for the E526V Mutation in Fibrinogen A Alpha-Chain Amyloidosis: The First Report

Table 2

Laboratory data.

Parameter/date	02.14.2006	04.07.2009	08.17.2010	08.14.2012	11.26.2012	12.05.2012
Urea (mg/dL)	69	41	89	136	135	188
Creatinine (mg/dL)	0.80	0.75	1.03	1.22	1.44	4.62
Creatinine clearance (mL/min/1.73 m^2)	67.9	84.7	68.3	45.9	37.6	9.2
Albumin (g/L)	43.0		45.7
HbA1c (%)			5.9
Uric acid (mg/dL)		6.7	8.9	7.0
Total bilirubin (mg/dL)	0.79	0.60	0.60	0.72	1.13	0.96
AST (U/L)	21	23	23	19	14	22
ALT(U/L)	19	14	20	15	2	12
ALP (U/L)	102	106	134	139	160	170
GGT (U/L)	90	86	88	81	106	65
Sodium (mmol/L)	144		134	136	132	122
Potassium (mmol/L)	4.73		4.17	4.50	4.87	5.73
Chloride (mmol/L)	106		96	101	96	98
Calcium (mmol/L)	2.52		2.56			2.02
Phosphorus (mmol/L)	1.03		1.18			2.09
iPTH (pg/mL)	75	80	103
Total cholesterol (mg/dL)	203	207	196	155
Triglycerides (mg/dL)	127	78	105	111
NT-proBNP (pg/mL)					14 056
CRP (mg/dL)						85.62
Cyclosporine (ng/mL)		80.5	94.7			130.2
Proteinuria (g/24 h)	0.15	0.90	0.51

HbA1c: glycated hemoglobin; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transferase; iPTH: intact parathyroid hormone; NT-proBNP: N-terminal pro-B-type natriuretic peptide; CRP: C-reactive protein.