Case Report

Minimal Change Disease as a Secondary and Reversible Event of a Renal Transplant Case with Systemic Lupus Erythematosus

Table 1

Laboratory findings 6 months after renal transplantation, at the start of proteinuria and creatinine rise.

CBC

Hemoglobin (g/dL)11.9
Hematocrit (%)36.8
WBC (109/L)3.6
RBC (1012/L)4.37
PLT (109/L)325
ANC (109/L)2.9
ALC (109/L)0.4

Metabolic panel

Serum sodium (mmol/L)136
Serum potassium (mmol/L)4.3
Serum chloride (mmol/L)107
Serum CO2 content (mmol/L)20
Serum calcium (mg/dL)9.3
Serum phosphorus (mmol/L)3.5
Anion gap (mmol/L)9
Serum creatinine (mg/dL)1.48
Serum urea nitrogen (mg/dL)22
Serum glucose (mg/dL)86

Liver function tests

Serum total protein (g/dL)7
Serum albumin (g/dL)4.4
Serum LDH (u/L)178
Serum bilirubin total (mg/dL)0.3
Serum bilirubin direct (mg/dL)0.1
Serum ALP (u/L)88
AST (u/L)17
ALT (u/L)12
INR1
Prothrombin time (s)10.3

Others

Serum tacrolimus FK506 (ug/L)7.7
Serum uric acid (mg/dL)5.7
Creatine kinase (u/L)143

SLE serology

ANA by IFBorderline
ANA titer/IF pattern1 : 40/diffuse

Blood cultures

Parvovirus B19Not detected
Adenovirus AntibodyNot detected
BK virus PCRNot detected
CMV virus PCR (copies/mL)<200
EBV virus PCR (copies/mL)<200

Urinalysis

Urine colorYellow
Urine appearanceCloudy
Urine protein (mg/dL)924
Urine creatinine (mg/dL)202.8
RBCs4–10
WBCs10–25
Urine bacteriaModerate
Urine bloodNegative
Urine ketonesNegative
Urine glucoseNegative
Urine pH6
Urine bilirubinNegative
Urine specific gravity1.024
Urine nitriteNegative
Urine leukocyte esteraseNegative
Urine cultureNo growth of clean catch (<1,000 CFU/mL)