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Case Reports in Nephrology
Volume 2016, Article ID 1358625, 4 pages
Case Report

Successful Pregnancy Using the NxStage Home Hemodialysis System

1Division of Nephrology, Thomas Jefferson University, 833 Chestnut Street, Suite 700, Philadelphia, PA 19107, USA
2Department of Obstetrics and Gynecology, Thomas Jefferson University, 833 Chestnut Street, 1st Floor, Philadelphia, PA 19107, USA

Received 25 November 2015; Revised 9 January 2016; Accepted 12 January 2016

Academic Editor: Helmut H. Schiffl

Copyright © 2016 Yasmin Brahmbhatt et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pregnancy in the setting of the uremic milieu of renal disease has a lower success rate than in the normal population and is a rare event. While intensified renal replacement therapy (RRT) during pregnancy can lead to improved outcomes, most studies have focused on nocturnal hemodialysis as the main RRT in pregnancy. Although thousands of patients use the home NxStage System One short daily hemodialysis (SDHD) machine in the United States, pregnancy outcomes with this therapy are unknown. The NxStage System One uses low-volume dialysate and hence small and middle molecule clearance may differ compared to conventional therapies and affect pregnancy outcomes. We report a case of a successful conception and pregnancy using the home NxStage system. The NxStage system may provide an alternative to the more routinely used NHD or standard SDHD therapies for women of childbearing age.