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Case Reports in Nephrology
Volume 2016 (2016), Article ID 4186086, 6 pages
http://dx.doi.org/10.1155/2016/4186086
Case Report

Granulomatous Interstitial Nephritis Presenting as Hypercalcemia and Nephrolithiasis

1Department of Medicine, Mount Sinai St. Luke’s-Roosevelt Hospital Center, New York, NY 10025, USA
2Department of Pathology, Mount Sinai St. Luke’s-Roosevelt Hospital Center, New York, NY 10025, USA
3Department of Medicine, Division of Nephrology, Mount Sinai St. Luke’s-Roosevelt Hospital Center, New York, NY 10025, USA

Received 30 November 2015; Accepted 29 December 2015

Academic Editor: Ze’ev Korzets

Copyright © 2016 Saika Sharmeen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We report a case of acute kidney injury as the initial manifestation of sarcoidosis. A 55-year-old male was sent from his primary care physician’s office with incidental lab findings significant for hypercalcemia and acute kidney injury with past medical history significant for nephrolithiasis. Initial treatment with intravenous hydration did not improve his condition. The renal biopsy subsequently revealed granulomatous interstitial nephritis (GIN). Treatment with the appropriate dose of glucocorticoids improved both the hypercalcemia and renal function. Our case demonstrates that renal limited GIN due to sarcoidosis, although a rare entity, can cause severe acute kidney injury and progressive renal failure unless promptly diagnosed and treated.