Interferon Induced Focal Segmental Glomerulosclerosis

Figure 1

(a) A glomerulus with collapsing FSGS exhibits global wrinkling and retraction of the glomerular basement membranes and diffuse swelling and proliferation of overlying visceral epithelial cells (Jones methenamine silver). (b) In this glomerulus with collapsing FSGS, some of the podocytes are detached from the glomerular basement membrane and lie free within the urinary space (periodic acid Schiff). Magnifications: 100 in (a) and 400 in (b).

(a)

(b)