Anticoagulant Related Nephropathy Induced by Dabigatran

Figure 2

Kidney biopsy histopathology I. (a) Kidney biopsy shows presence of abundant RBCs (box) and RBC casts (arrows) (Periodic Acid Schiff stain, Light Microscopy, Magnification: X200). (b) Kidney biopsy shows acute tubular injury with loss of brush borders, attenuated tubular epithelium, and reactive epithelial changes. RBC casts (arrows) indicate significant hemorrhage in tubules. The mesangium of glomerulus is minimally expanded with no evidence of proliferation. (Periodic Acid Schiff Stain, Light Microscopy, Magnification: X200.)

(a)

(b)