Tubulocystic Renal Cell Carcinoma of the Native Kidney in a Renal Transplant Recipient: A Rare Case Report

Figure 2

(a) Well-demarcated lesion of small- to intermediate-sized tubules admixed with cystically dilated tubules (solid thick arrows). (b) Tubules and cysts comprising a single epithelial layer of flat to hobnail-shaped cells with abundant, pink cytoplasm and large nuclei with prominent nucleoli (dashed thick arrows). The stroma was fibrotic and paucicellular, while mitotic activity was low to absent. No papillary architecture or epithelial cell clearing was observed. (c) Immunohistochemical stain for CK7 showed patchy reactivity (thin solid arrows) in the lesional areas. (d) CD10 showed strong reactivity.