Galactose-Deficient IgA1 Deposits in Clear Cell Renal Cell Carcinoma-Related Henoch–Schönlein Purpura Nephritis

Figure 2

Findings of initial kidney biopsy: (a) a representative glomerulus with global endocapillary proliferation on periodic acid-Schiff stain; (b) a glomerulus with segmental mesangial and endocapillary proliferation (right side) and intracapillary pseudothrombi (<); (c) immunofluorescence staining of IgA shows global granular mesangial and capillary wall staining and a few intracapillary pseudothrombi (<); (d) electron microscopy shows many electron dense mesangial and subendothelial deposits with severe foot process effacement. Original magnification: 400X in (a–c) and 5000X in (d).

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(b)

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(d)