Can Antinuclear Antibodies (ANA) be Monoclonal?

Figure 2

Immunofluorescence findings in a patient with IgG lambda monoclonal gammopathy. (a) Positive stain for IgG in the nuclei. (b) Negative stain for kappa light chain in the nuclei. (c) Positive stain for lambda light chain in the nuclei. (d) Negative stain for IgG1 subclass in the nuclei. (e) Positive stain for IgG2 subclass in the nuclei. (f) Negative stain for IgG3 subclass in the nuclei. (g) Negative stain for IgG4 subclass in the nuclei. Magnification 200x.

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