Can Antinuclear Antibodies (ANA) be Monoclonal?

Table 2

Nuclear staining pattern by immunofluorescence.

Case #	IgG1	IgG2	IgG3	IgG4	Kappa	Lambda	Others
1	1+	0	0	0	1+	0
2	1+	0	0	0	1+	0
3	1+	0	0	0	1+	0
4	0	1+	0	0	0	1+
5	2+	±	0	0	2+	±
6					±	2+	IgA 2 + n
7	2+	0	0	±	2+	±
8	0	0	1+	0	0	1+
9	2+	0	0	0	2+	0

Intensity of the staining was quantitated by a semiquantitative scale, where 0 represents absent; 1+ represents mild; 2+ represents moderate, and 3+ represents prominent staining. BL, baseline; SCr, serum creatinine; ANA, antinuclear antibody; SPEP/UPEP, serum and urine protein electrophoresis.