Case Series
Can Antinuclear Antibodies (ANA) be Monoclonal?
Table 3
Main histologic findings in the kidney biopsies.
| Case # | # of glomeruli | # of globally sclerosed glomeruli | IFTA | Pathologic diagnosis |
| 1 | 15 | 7 | Prominent | Active focal crescentic and necrotizing glomerulonephritis | 2 | 8 | 0 | Mild | Mild diffuse proliferative glomerulonephritis with “full-house” glomerular immune complex deposition. | 3 | 69 | 28 | Moderate | Focal crescentic glomerulonephritis with fibrous crescents and predominantly C3-containing mesangial immune complex deposits in the glomeruli | 4 | 18 | 10 | Moderate | Moderate chronic kidney injury with increased number of globally sclerosed glomeruli | 5 | 3 | 1 | Moderate | Focal proliferative lupus nephritis (ISN/RPS class III (A/C)) | 6 | 5 | 1 | Moderate | Small amount of renal cortex with nonspecific findings | 7 | 7 | 0 | Moderate | Focal proliferative lupus nephritis with membranous lupus nephritis (ISN/RPS class III + V) | 8 | 8 | 1 | Mild | Membranous glomerulonephritis | 9 | 17 | 6 | Prominent | Advanced stage diabetic nephropathy with diffuse and nodular diabetic glomerulosclerosis. |
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