Calciphylaxis: A Long Road to Cure with a Multidisciplinary and Multimodal Approach

Table 2

Therapies used for the management of patients with calciphylaxis and mechanisms of action.

Therapies	Mechanism of action
Increased dialysis frequency	Clearance of uremic molecules [3, 4, 8]
Dialyzate calcium 1,25 mmol/L	Slowing down calcification [3, 4, 6]
Non-calcium-containing binders	Avoiding hypercalcemia—high phosphorus [3, 4, 9]
Cinacalcet	Controlling parathyroid hormones [10, 11]
Sodium thiosulfate	Inhibiting calcification [12, 13]
Debridement	Ulceration treatment [6]
Hyperbaric oxygen therapy	Tissue oxygenation—wound healing [8, 14]