Case Report
Ineffectiveness of Intermittent Hemodialysis in a Critically Ill COVID-19 Patient: A Case of Persistent Heparin-Induced Hyperkalemia
Table 1
Summary of laboratory evaluations and relevant trend during hospitalization.
| Date | Reference | July 7, 2021 | July 9, 2021 | July 10, 2021 | July 12, 2021 | July 14, 2021 | July 17, 2021 | July18, 2021 | July 19, 2021 | July 20,2021 | July 21,2021 | July 22, 2021 | July 23, 2021 | July 24, 2021 | July 25, 2021 | July 26,2021 |
| Arterial pH | 7.35–7.45 | 7.62 | 7.45 | 7.50 | 7.50 | 7.45 | 7.5 | 7.41 | 7.44 | 7.29 | 7.33 | 7.36 | 7.37 | 7.38 | 7.35 | 7.16 | pCO2 (mmHg) | 35–45 | 27.4 | 47.8 | 49.7 | 43.3 | 43 | 27 | 44.7 | 52.9 | 61.3 | 53 | 48 | 83 | 84 | 88 | 63 | HCO3 (mmol/L) | 22–32 | 27.4 | 33.7 | 39.4 | 33.8 | 30.6 | 27 | 28 | 32.8 | 24.9 | 25 | 28 | 28 | 26 | 26 | 25.8 | Hemoglobin (g/dl) | 12.5–15 | | | 15.9 | | 16.3 | 14.8 | 14.4 | | 14.3 | | 13.6 | | | | 12.0 | White blood cell count (elements/mm3) | 4,000–10,000 | 13870 | | 13080 | | 14940 | 24370 | 18100 | | 18.500 | | 25.570 | | | | 27.150 | Glycated hemoglobin (%) | 4–5.6 | 7.1 | | | | | | | | | | | | | | | Fibrinogen (g/L) | 2–4 | 5.5 | | | | | | | | | | | | | | | D-dimer (ng/mL) | 220–500 | ˃10000 | | | 1224.2 | | | | | | | | | | | | Procalcitonin (ng/mL) | ˂0.15 | 0.18 | | 0.25 | 0.17 | 0.10 | 0.28 | | | 0.74 | | | 0.41 | | | 0.98 | CRP (mg/L) | ˂6 | 147 | | 66 | 41 | 23 | 105 | | | 297 | | | 71 | | | 132 | Blood urea (mmol/L) | 2.5–7.5 | 10.6 | | | 14 | 14.3 | 18.6 | 19.5 | 14.9 | 19.8 | 26.4 | | 25.8 | | | 20.3 | Serum creatinine (μmol/L) | 53–120 | 69 | | | 95 | 75 | 126 | 123 | 94 | 170 | 292 | | 336 | | | 290 | Sodium (mmol/L) | 135–145 | 129 | 139 | 138 | 139 | 131 | 129 | 134 | | 134 | 136 | 134 | 135 | 135 | 134 | 137 | Potassium (mmol/L) | 3.0–5.0 | 4 | 4.5 | 4.8 | 4.7 | 4.8 | 4.2 | 4.5 | | 5.1 | 6.6 | 6.4 | 6.0 | 6.0 | 6.4 | 5.9 | Ionized calcium (mmol/L) | 1.15–1.30 | 1.09 | | | 1.20 | | | | | | | | | | | | Aspartate amino transferase (UI/L) | 6–34 | 32 | | | | | | | | | 45 | | | | | | Alanin amino transferase (UI/L) | 8–38 | 29 | | | | | | | | | 41 | | | | | | Uric acid (μmol/L) | 150–420 | 320 | | | | | | | | | 332 | | | | | | Phosphorus (mmol/L) | 0.97–1.45 | 1.10 | | | | | | | | | 1.7 | | | | | | LDH (UI/L) | 140–280 | 936 | | | | 674 | 450 | | | | 441 | | | | | | CK (UI/L) | 22–198 | 101 | | | | | 97 | | | | 82 | | | | | | Troponin (Abbot) (ng/mL) | 0–0.4 | 258.3 | 138.2 | | | | | | | | | | | | | | Brain natriuretic peptide (pg/mL) | ˂300 | 2071 | 770 | | | 2179 | 4334 | 3232 | 1040 | 1027 | 2169 | | | | | | PCR-COVID-19 | | + | | | | — | | | | | | | | | | — | Antigen/IgG COVID-19 | | — | | | | | | | | | | | | | | | Antigen/IgM COVID-19 | | + | | | | | | | | | | | | | | |
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Day of intubation. Start of hemodialysis. |