A Case of Castleman’s Disease during the Long-Term Course of Membranous Nephropathy

Figure 2

Lymph node pathology. Light microscopic appearance of inguinal lymph node obtained by needle biopsy reveals diffuse interfollicular plasma cell infiltration (hematoxylin and eosin staining (HE)) (a). As hyaline vascular proliferation was not evident, this case present plasma cell type of MCD. Immunohistochemistry reveals CD20-positive lymphocytes in the follicular region (b), while significant CD138-positive plasma cells exist in the interfollicular region (c).

(a)

(b)

(c)