Pembrolizumab Induced Calcitriol-Mediated Hypercalcemia

Figure 1

This graph shows the trend in the levels of calcium and creatinine throughout the patient’s hospitalization as various treatments were provided as labeled above. “Day 0” is one day prior to pembrolizumab administration. “Day 94” represents post hospitalization recheck of laboratory studies. The X axis represents time measured in days. The left Y axis illustrates creatinine levels in mg/dL. The right Y axis demonstrates the calcium levels in mg/dL. The green dashed lines indicate the start dates for denosumab and the blue dash vertical dash lines indicate the start dates for methylprednisolone.