Case Reports in Neurological Medicine / 2011 / Article / Tab 1

Case Report

Neuropsychiatric Outcome of an Adolescent Who Received Deep Brain Stimulation for Tourette's Syndrome

Table 1

Results of neurologic examination, neurocognitive testing, and psychotropic medication load pre- and postelectrode implantation.

Electrode placementBilateral centromedian parafascicular complex (CM-Pf)PreimplantationPostimplantation

Neurologic testingYGTSS ScoresaDate of testing
Date of testing

Number motor21
Number phonic10
Frequency motor51
Frequency phonic20
Intensity motor52
Intensity phonic20
Complexity motor20
Complexity phonic10
Interference motor50
Interference phonic20
Overall impairment5010
Global severity7714

Neurocognitive testingWAIS-III/IVbDate of testing
Date of testing

Full scale IQ7674
Verbal comprehension8478
Perceptual organization7673
Working memory8086
Processing speed7681

Psychosocial testingBASCcDate of testing
Date of testing

Clinical scalesHyperactivity6859
Conduct problems5656
Attention problems6355

Adaptive scalesAdaptability3349
Social skills5262
Activities daily living3245
Functional communication3953

Composite scalesExternalizing problems6054
Internalizing problems8156
Behavioral symptoms index6850
Adaptive skills3753

Psychiatric evaluationPsychotropic medicationsdDate of evaluation
Date of evaluation

Aripiprazole 30 mg
Diazepam 20 mg
Divalproex sodium 3000 mg
Guanfacine 2.5 mg
Quetiapine 400 mg
Risperidone 1.5 mg
Risperidone 6 mg
Guanfacine 2 mg

aYGTSS:Yale Global Tic Severity Scale.
bWAIS-III/IV: Wechsler Adult Intelligence Scale-III/IV—Standard scores with a general population mean of 100 and a standard deviation of 15 are reported here. The WAIS III was administered preimplantation. The WAIS IV was administered postimplantation.
cBASC: Behavior Assessment System for Children, Second Edition Ages 12–21; raw test scores reported here. A score reduction on items within clinical scales reflects relative improvement in the different measures of psychiatric symptomatology, whereas a score increase on items within adaptive scales reflects a relative improvement on different measures of adaptive functioning. Within the composite scales, a score reduction in the domains of externalizing symptoms, internalizing symptoms, and behavioral symptoms reflects relative improvement, whereas a score increase in the adaptive skills domain reflects relative improvement.
dPsychotropic medications reported as maximum daily dosages prescribed to patient.

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