Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Neurological Medicine
Volume 2012, Article ID 121470, 7 pages
http://dx.doi.org/10.1155/2012/121470
Case Report

Multiple Pulmonary Metastases following Total Removal of a Bilateral Parasagittal Meningioma with Complete Occlusion of the Superior Sagittal Sinus: Report of a Case

1Department of Pathology, Jikei University School of Medicine Kashiwa Hospital, 163-1 Kashiwa-shita, Chiba 277-8567, Kashiwa, Japan
2Department of Neurosurgery, Jikei University School of Medicine Kashiwa Hospital, 163-1 Kashiwa-shita, Chiba 277-8567, Kashiwa, Japan
3Department of Thoracic Surgery, Jikei University School of Medicine Kashiwa Hospital, 163-1 Kashiwa-shita, Chiba 277-8567, Kashiwa, Japan
4Department of Neurosurgery, Jikei University School of Medicine, Chiba 277-8567, Kashiwa, Japan

Received 17 April 2012; Accepted 30 May 2012

Academic Editors: K. Arnautovíc, P. Berlit, and H. Kocaeli

Copyright © 2012 Masataka Nakano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Pulmonary metastases of benign meningiomas are extremely rare. The case of a 34-year-old man with bilateral parasagittal meningioma who developed pulmonary metastases is described. The meningioma was an enormous hypervascular tumor with invasion of the superior sagittal sinus. The tumor was resected completely and histologically diagnosed as transitional meningioma. The Ki-67 labeling index was 5%. Four months after operation, the patient subsequently developed bilateral multiple lung lesions later identified as metastases. The lung lesions were partially removed surgically and histologically diagnosed as meningothelial meningioma WHO grade I. The Ki-67 labeling index was 2%. The histological findings demonstrated that the tumor occupied the arterial lumen and the perivascular space, suggesting that pulmonary tumors might metastasize via the vascular route. The histopathological features and mechanisms of metastasizing meningiomas are reviewed and discussed.