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Case Reports in Neurological Medicine
Volume 2013, Article ID 263718, 6 pages
http://dx.doi.org/10.1155/2013/263718
Case Report

Oncogenic Brain Metazoan Parasite Infection

1Department of Surgery, Division of Neurological Surgery, School of Medicine, University of Missouri, Columbia, MO, USA
2Department of Pathology, School of Medicine, University of Missouri, Columbia, MO, USA

Received 28 May 2013; Accepted 19 August 2013

Academic Editors: A. Amirjamshidi, F. T. Mangano, and M. Turgut

Copyright © 2013 Angela N. Spurgeon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship.