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Case Reports in Neurological Medicine
Volume 2013, Article ID 371929, 2 pages
Case Report

Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson’s Disease

1Department of Neurology, Ondokuz Mayis University, Samsun, Turkey
2Department of Neurosurgery, Faculty of Medicine, Ondokuz Mayis University, 55200 Samsun, Turkey
3Department of Neurosurgery and Neuroscience, Maastricht University Medical Center, P. Debyelaan 25, 6202 AZ Maastricht, The Netherlands
4Department of Psychology, Ondokuz Mayis University, Samsun, Turkey
5Department of Psychiatry, Ondokuz Mayis University, Samsun, Turkey

Received 5 November 2013; Accepted 4 December 2013

Academic Editors: T. K. Banerjee, S. T. Gontkovsky, and N. S. Litofsky

Copyright © 2013 Dursun Aygun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In advanced Parkinson's disease (PD), deep brain stimulation (DBS) may be an alternative option for the treatment of motor symptoms. Side effects associated with subthalamic nucleus (STN) DBS in patients with PD are emerging as the most frequent sensory and motor symptoms. DBS-related syncope is reported as extremely rare. We wanted to discuss the mechanisms of syncope associated with STN DBS in a patient with Parkinson's disease. Case report. Sixty-three-year-old female patient is followed up with diagnosis of idiopathic Parkinson's disease for 6 years in our clinic. The patient has undergone STN DBS due to painful dystonia and drug resistant tremor. During the operation, when the left STN was stimulated at 5 milliampere (mAmp), the patient developed presyncopal symptoms. However, when the stimulation was stopped symptoms improved. During the early period after the operation, when the right STN was stimulated at 1.3 millivolts (mV), she developed the pre-yncopal symptoms and then syncope. Our case shows that STN DBS may lead to directly autonomic symptoms resulting in syncope during stimulation-on (stim-on).