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Case Reports in Neurological Medicine
Volume 2013 (2013), Article ID 809151, 2 pages
Case Report

Marked Seizure Reduction after MCT Supplementation

Neurology Department, Vanderbilt University Medical Center, A-0118 MCN 2551, Nashville, TN 37232-2551, USA

Received 23 October 2013; Accepted 12 November 2013

Academic Editors: J. L. González-Gutiérrez, F. C. Henderson, F. Micheli, and J. B. White

Copyright © 2013 Raed Azzam and Nabil J. Azar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report the case of a 43-year-old man with history of nonsurgical partial epilepsy who previously failed multiple trials of antiepileptic drugs. Medium-chain triglycerides (MCT) were added to his regular diet in the form of pure oil. Subsequently, his seizure frequency was markedly reduced from multiple daily seizures to one seizure every four days. His seizures recurred after transient discontinuation of MCT over a period of ten days. His seizure improvement was achieved at a dose of four tablespoons of MCT twice daily with no reported side effects. He developed significant diarrhea and flatulence at higher doses. We conclude that MCT oil supplementation to regular diet may provide better seizure control in some patients. MCT oil supplementation may be a more tolerable alternative to the standard ketogenic diet.