Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Neurological Medicine
Volume 2013, Article ID 812158, 6 pages
Case Report

Cerebral Aneurysms: A Rare Feature of Behçet's Disease—A Case Report and Review of the Literature

1Department of Endocrinology and Internal Medicine, Tahar Sfar University Hospital of Mahdia, Hiboun District, 5100 Mahdia, Tunisia
2Department of Neurology, Fattouma Bourguiba University Hospital of Monastir, 1st June Street, 5000 Monastir, Tunisia
3Department of Medical Imagery, Tahar Sfar University Hospital of Mahdia, Hiboun District, 5100 Mahdia, Tunisia

Received 8 June 2013; Accepted 10 July 2013

Academic Editors: K. Arnautovíc, Ö. Ateş, and H. Ikeda

Copyright © 2013 Samia Younes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Behçet's disease (BD) is a multisystem vascular inflammatory disease with several clinical manifestations. Intracranial aneurysms are an extremely rare but nevertheless severe complication of BD. We report a case of a 44-year-old man. The diagnosis of BD was made based on the presence of recurrent oral aphthous ulcers and positive human leukocyte antigen (HLA-) B51 in the absence of evidence of other diseases. MRI showed an ancient ischemic right capsulolenticular lesion, subacute white matter hypersignals of the left capsule lenticular region, and multiple arterial aneurysms. The patient underwent two-month systemic high-dose corticosteroids and immunosuppressive therapy associated with severe neurological deficiency upon admission and severe impairment upon discharge. A thorough review of the literature showed 20 case reports of intracranial aneurysms in BD.