Case Report

Late Onset Atypical Pantothenate-Kinase-Associated Neurodegeneration

Table 2

Published reports of late adult-onset atypical PKAN.

ReferenceAge of onsetClinicalEye-of-the- TigerPANK2 mutation

Vasconcelos et al. 2003 [7]
36Dysarthria, tongue atrophyYesYes
Antonini et al. 2006 [8]30Choreoathetosis, postural tremor, personality changes, and paranoia
YesYes
Seo et al. 2009 [9]
35ParkinsonismYesYes
Aggarwal et al. 2010 [10]
37Postural/action tremorYesYes
del Valle-López et al. 2011 [5]30Acute psychosis, clumsiness, and frequent fallsYesYes