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Case Reports in Neurological Medicine
Volume 2014, Article ID 546817, 5 pages
Case Report

Multiple Sclerosis and Oligodendroglioma: An Exceptional Association

1Neurology Department, Centro Hospitalar Vila Nova Gaia/Espinho, 4434-502 Vila Nova de Gaia, Portugal
2MS Clinic, Neurology Department, Centro Hospitalar São João, 4440-563 Porto, Portugal
3Neurosurgery Department, Centro Hospitalar São João, 4440-563 Porto, Portugal
4Faculty of Medicine of Porto University, 4200-319 Porto, Portugal
5Pathological Anatomy Department, Centro Hospitalar São João, 4440-563 Porto, Portugal
6Faculty of Health Sciences, Fernando Pessoa University, 4249-004 Porto, Portugal

Received 21 April 2014; Revised 25 June 2014; Accepted 16 July 2014; Published 7 August 2014

Academic Editor: Andreas K. Demetriades

Copyright © 2014 Ana Teresa Carvalho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The cooccurrence of multiple sclerosis (MS) and oligodendroglioma is very rare. We present a 43-year-old male patient with the diagnosis of MS lasting for 14 years who developed seizures and right hemiparesis; cerebral MRI revealed an already known extensive lesion, previously misdiagnosed as tumefactive demyelinating lesion. Cerebral biopsy leads to oligodendroglioma diagnosis, successfully treated with radiotherapy. The diagnosis of a brain tumor in a MS patient is challenging. The atypical clinical and radiological features are the key for accurate diagnosis. In such cases, a brain tumor has to be kept in mind no matter how rare this association is.