A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles

Figure 2

The mutation analysis of the NOTCH3 gene. The sequence analysis showed a missense mutation, GGG to CGG at the nucleotide 4039 of exon 24 (arrow). The DNA mutation numbering is based on the cDNA sequence (GenBank accession number NM_000435.2), with +1 corresponding to the A of the translational initiation site.