Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Neurological Medicine
Volume 2015, Article ID 543927, 4 pages
Case Report

Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma

1Department of Neurology, Ishibashi General Hospital, Shimotsuke 329-0596, Japan
2Department of Neurology, Jichi Medical University, Shimotsuke 329-0498, Japan
3Department of Hematology, Ishibashi General Hospital, Shimotsuke 329-0596, Japan

Received 8 June 2015; Accepted 15 September 2015

Academic Editor: Giuliana Galassi

Copyright © 2015 Yoshihide Sehara et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An 80-year-old man was admitted for acute subdural hematoma caused by a mild brain injury. His coagulation test showed an isolated prolongation of activated partial thromboplastin time (aPTT). Though the subdural hematoma did not progress, oozing bleed from the wound of tracheostomy continued. Failure of correction on aPTT mixing test supported the presence of an inhibitor to a coagulation factor. Once the diagnosis of acquired hemophilia A (AHA) was made, steroid therapy was performed, which leads him to complete remission of AHA. Isolated prolongation of aPTT can be the key to diagnose a rare coagulopathy, such as AHA.