Case Report

Eosinophilic Granulomatosis with Polyangiitis Presenting as Acute Polyneuropathy Mimicking Guillain-Barre Syndrome

Table 1

Characteristics of patients with EGP presenting as GBS.

ReferenceAge (sex)Clinical manifestationsLaboratory findings NCSOther TreatmentOutcome

[7]58 MSymmetric weakness, hyporeflexia, and asthmaEosinophilia, elevated ERS, and p-ANCA+Mixed demyelinating polyneuropathy and multifocal absent F-wavesLung infiltratesP, CyC, and SExpired
[8]57 MSymmetric weakness and hyporeflexia p-ANCA+ and elevated ERSDemyelinating polyneuropathy and multifocal absent F-wavesNephritisSImproved

[9]51 FSymmetric weakness, hyporeflexia, asthma, and nasal polyposisEosinophilia, elevated CRP, and ANCA−Motor asymmetric axonal polyneuropathy and multifocal absent F-waves IvIG and SImproved

[10]74 MSymmetric weakness, hyporeflexia, and asthmaEosinophiliaMixed demyelinating polyneuropathyS and CyCImproved

[11]64 FAsymmetric weakness, hyporeflexia, asthma, diplopia, and sinusitisElevated ESR, eosinophilia, and p-ANCA+Motor axonal and demyelinating polyneuropathy and multifocal absent F-waves Multiorgan diseaseIvIG, CyC, and SExpired

Present case36 FSymmetric weakness, hyporeflexia, asthma, purpura, and pansinusitisElevated ESR, eosinophilia, and p-ANCA+Mixed axonal asymmetric polyneuropathyS and CyCImproved

NCS: nerve conduction studies; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; IvIG: intravenous immunoglobulin; CyC: cyclophosphamide; P: plasmapheresis; S: steroids.