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Case Reports in Neurological Medicine
Volume 2016 (2016), Article ID 1972594, 4 pages
Case Report

Isolated Intracranial Rosai-Dorfman Disease

1Department of Pathology, Square Hospitals Ltd., Dhaka 1205, Bangladesh
2Department of Neurosurgery, Green Life Medical College and Hospital, Dhaka 1205, Bangladesh
3Department of Pathology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka 1000, Bangladesh
4Department of Pathology, Dhaka National Medical College, Dhaka 1100, Bangladesh

Received 23 October 2015; Accepted 4 January 2016

Academic Editor: Mehmet Turgut

Copyright © 2016 Md. Taufiq et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Rosai-Dorfman disease (RDD) is a benign histiocytic proliferative disorder of unknown etiology. This rare condition commonly causes massive cervical lymphadenopathy. Intracranial RDD without any nodal involvement is extremely rare. Case Report. A young Bangladeshi male complained of bilateral complete blindness with left sided deafness for about three years. There was no lymphadenopathy. MRI and CT scan of brain suggested an inflammatory/neoplastic (?meningioma) lesion located at left parasellar region which extended frontally to encircle both optic nerves and also to left prepontine area. Histopathologically the lesion was diagnosed as RDD. The patient was treated with steroid and significant clinical improvement observed. Conclusion. The prognosis of intracranial RDD is not poor. It can be treated with surgery with or without corticosteroids, chemotherapy, and so forth. But as the condition is extremely rare and often misdiagnosed, the clinician, radiologist, and histopathologist should have a suspicion in their mind about the possibility of RDD.