Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis

Table 1

Serum thrombophilia and autoimmune tests.

Test	Result
Serum Venereal Disease Research Laboratory (VDRL)	Reactive, titres of 1 : 64
Serum Treponema pallidum particle agglutination (TPPA) test	Reactive
Anti-cardiolipin IgM antibody	48.93 (MPL^1): likely false positive; (Lower normal limit for the laboratory is 12.5 MPL, indeterminate: 12.5–20)
Anti-cardiolipin IgG antibody	<9.40 [GPL]; Negative < 15 GPL^2
Anti-thrombin III	Normal
Protein C	Normal
Protein S (functional)	Low at 60% (range: 75–130%)
Factor V Leiden mutation	Not detected
Anti-nuclear antibodies (ANA)	Positive at titres of 1 : 80
Anti-double stranded DNA	Negative
Anti-neutrophil cytoplasmic antibodies (ANCA)	Negative
(anti-myeloperoxidase, anti-proteinase 3)
Extracted nuclear antigen (ENA) profile	Negative for anti-SSA^3, anti-SSB^4, anti-Scl70^5, anti-ribonucleic protein, anti-Smith antigen, and anti-Jo1^6

microgram/ml IgM, microgram/ml IgG, ³anti-Sjögren’s syndrome-related antigen A, ⁴anti-Sjögren syndrome type B antigen, ⁵anti-topoisomerase I, and ⁶anti-histidyl tRNA synthetase.