Late-Onset Pompe Disease with Nemaline Bodies

Figure 2

Light microscopy of the left vastus lateralis ((a), resin; (b)-(f), cryostat). (a) Vacuoles filled with polysaccharide material (PAS, x 40); (b) vacuoles stained positively for acid phosphatase reaction (x 20); (c) ATPase histochemistry at pH 4.3 revealed selective atrophy of type 1 fibers (x 40); (d) vacuoles are present predominantly in type 1 fibers (x 40); (e)-(f) atrophic fibers containing numerous nemaline bodies (Gomori trichrome, x 100).

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