Exercise Combined with Electrotherapy Enhances Motor Function in an Adolescent with Spinal Muscular Atrophy Type III

Table 1

Outcome measures.

(a)

	Thigh circumference (cm)				MIVC (Kg)		Tinetti scale			HFMSE
	10 cm; from patella		15 cm; from patella
	Right	Left	Right	Left	Right	Left	Gait	Balance	Total
T0	38.9	39.0	40.3	40.5	1.7	0.8	7/16	8/12	15/28	35/66
T1	39.6	39.5	40.6	40.8	2.2	2.0	11/16	10/12	21/28	NE
T2	40.4	40.2	41.2	41.1	2.9	2.3	11/16	12/12	23/28	42/66

(b)

	HR; (bpm)		VO2; (ml/Kg/min)		Measured METs	Standard METs
	Basal	Peak	Basal	Peak
T1	87	101	3.12	8.11	2.6	2.3
T2	86	112	3.03	10.9	3.4	3.1

(a) T0=baseline (beginning of Phase I); T1=after 8 weeks of treatment (end of Phase I; beginning of Phase II); T2=end of treatment (end of Phase II); MVIC=maximal voluntary isometric contraction; HFMSE=Hammersmith Functional Motor Scale-Expanded; NE: not evaluated; (b) Values calculated during the first and the last session of the FES-assisted cycling exercise program; HR=heart rate; VO₂=oxygen consumption; and METs=metabolic equivalents of task (measured METs were calculated as the ratio of the peak metabolic rate to the measured basal metabolic rate in quite sitting position; standard METs were calculated as the ratio of the peak metabolic rate to a standard resting metabolic rate equal to 3.5 ml/Kg/min).