Early-Onset Alzheimer’s Disease Masquerading as Catatonia

Table 1

Laboratory tests performed.

Test	Result
Initial testing
Complete metabolic panel and liver function tests	Within normal limits
Complete blood count	Within normal limits
Urine analysis	Within normal limits
Thyroid-stimulating hormone	0.97 (0.27–4.20) uIU/mL
Chest X-ray	Unremarkable
Urine toxicology	Amphetamines screen: negative
	Barbiturates screen: negative
	Cocaine screen: negative
	Benzodiazepine screen: negative
	THC screen: negative
	Methadone: negative
	Oxycodone screen: negative
	Opiates screen: negative
	Phencyclidine screen: negative
Secondary workup
HIV 1/2 rapid antibody	Nonreactive
Rapid plasma reagin	Negative
Sedimentation rate	10 (0–20) mm/hr
C-reactive protein	<0.03 (<0.5) mg/dL
Autoimmune panel	Antinuclear antibody: negative
	Antineutrophil cytoplasmic Ab: negative
	C4, 29 (10–40) mg/dL
	C3, 139 (90–180) mg/dL
	SSA Ab <0.3 (0.0–6.9) U/mL
	SSB Ab <0.3 (0.0–6.9) U/mL
	Anti-DSDNA 7 (0–24) IU
	Smith antibody 1.5 (0.0–6.9) U/mL
	Anti-TPO: negative
	Mayo dementia, autoimmune evaluation panel: negative
Cerebrospinal fluid studies
Color and clarity	Clear and colorless
White blood cells	1 (0–10) mm^3
Red blood cell count	1 mm^3
Protein	19 (15–45) mg/dL
Glucose	64 (40–70) mg/dL
Myelin basic protein	Negative
Oligoclonal bands	Negative
Cytology	No atypical lymphoid cells
Mayo paraneoplastic panel	Negative
Mayo dementia, autoimmune evaluation panel	Negative
Protein 14-3-3	<0.2
Neuronal specific enolase	Negative
VDRL	Negative