Treatment of a Woman with Inoperable Meningioma Using Mifepristone for 26 Years

Table 2

Hormonal dosages before and during mifepristone use.

Hormone^∗	Basal	After mifepristone
Cortisol 8 h (NV 4.3–22.4 ng/mL)	6.0	239
Cortisol 16 h (NV 2–15 ng/dL)	3.0	37
ACTH 8 h (NV up to 160 pg/mL)	90	420
ACTH 16 h (NV up to 50 pg/mL)	110	85
FSH (NV follicular phase 2.5–10.2 mIU/mL)	9.4	0,1^†	8.3^ǂ
LH (NV follicular phase 2.5–12 mIU/ml)	6.75	0,8^†	6.77^ǂ
Estradiol (NV 19.5–144 pg/mL)	151	—	35.8^ǂ
Progesterone (NV follicular phase < 1.4 ng/mL)	0.22	—
TSH (NV 0.6–4.5 mcUI/mL)	6.8	<0.01^§
T4 total (NV 5.2–12,7 mcg/dL)	6.47	—
T4 free (NV 0.72–1.72 ng/mL)	0.68	1.38^§
T3 total (NV 60–181 ng/dL)	92	—
Prolactin (NV up to 26 ng/mL)	76.8	17.0
IGF-1 (37–219 ng/mL)	90.6	91

^∗ACTH = adrenocorticotropic hormone; FSH = follicle-stimulating hormone; LH = luteinizing hormone; TSH = thyroid-stimulating hormone; IGF-1 = insulin growth factor 1. ^†Use of 0.625 mg equine-conjugated estrogen; ^ǂafter bilateral oophorectomy performed at age 57; ^§use of 100 mcg L-thyroxine.