Case Report

Vasculitic Tibial Mononeuropathy Associated with Inherited Immune Dysregulation: A Review of Tibial Mononeuropathies with Electrodiagnostic Considerations

Table 1

Electrodiagnostic data.

Nerve conductionAmplitude (µV or mV)Latency (ms)Conduction velocity (m/s)
RightLeftRightLeftRightLeft

Sural sensory
Stimulate calf, record ankle (14 cm distance)6.0 (6–47)7.2 (6–47)3.4 (3.2–4.2)3.4 (3.2–4.2)48.3 (>40)53.8 (>40)
Medial plantar sensory
Stimulate foot, record ankleNo responseNo response
Superficial peroneal sensory
Stimulate ankle, record foot (10 cm distance)5.63.82.83.1
Peroneal motor
Stimulate ankle, record EDB (9 cm distance)3.8 (2–12)3.3 (2–12)3.8 (3.3–6.1)4.1 (3.3–6.1)
Stimulate below knee, record EDB3.73.18.69.051.0 (41–56)48.0 (41–56)
Stimulate above knee, record EDB3.63.910.511.052.650.0
Tibial motor
Stimulate ankle, record AH (8 cm distance)0.3 (3–26)1.8 (3–26)6.0 (2.7–6.1)4.4 (2.7–6.1)
Temperatures: right calf: 34.8°C, left calf: 33.0°C

Needle electromyography
Spontaneous activityVoluntary activity
Muscle (right)Insertional activityPositive sharp waves and fibrillationsFasciculationsAmplitudeDurationPolyphasiaRecruitment
FDIPIncreasedSustained 3+00
Anterior tibialisSlightly increasedUnsustained 00NormalIncreased 2+Increased 2+Decreased 3+
Medial gastrocnemiusNormal00NormalNormalNormalDecreased 2+
SoleusIncreasedSustained 2+0NormalIncreased 2+Increased 2+Decreased 3+
Short head of bicepsNormal00NormalNormalNormalNormal
Gluteus mediusNormal00NormalNormalNormalNormal

Nerve conduction studies: sensory study values are recorded in µV, and motor study values are recorded in mV. Note the markedly decreased amplitude of the right tibial motor response as compared with the left. Reference lab values are indictaed in parentheses. EDB = extensor digitorum brevis; AH = abductor hallucis. Needle electromyography: note the marked denervation of the soleus with relative sparing of the medial gastrocnemius and normal short head of the biceps. All voluntary activity was performed by the patient with normal effort. FDIP = first dorsal interosseous pedis.