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Case Reports in Obstetrics and Gynecology
Volume 2012 (2012), Article ID 726732, 3 pages
Case Report

Fetal Arthrogryposis Secondary to a Giant Maternal Uterine Leiomyoma

1Department of Obstetrics, La Fe University Hospital, Bulevar Sur s/n, 46026 Valencia, Spain
2Department of Obstetrics, Regional Hospital of Vinaroz, Avenida de Gil de Atrocillo s/n, 12500 Castellon, Spain

Received 27 September 2012; Accepted 22 October 2012

Academic Editors: I. MacKenzie, P. McGovern, E. Shalev, and Y. Zalel

Copyright © 2012 José María Vila-Vives et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Arthrogryposis multiplex congenital is a rare condition defined as contractures in multiple joints at birth due to disorders starting in fetal life. Its etiology is associated with many different conditions and in many instances remains unknown. The final common pathway to all of them is decreased fetal movement (fetal akinesia) due to an abnormal intrauterine environment. Causes of decreased fetal movements may be neuropathic abnormalities, abnormalities of connective tissue or muscle, intrauterine vascular compromise, maternal diseases, and space limitations within the uterus. When the cause of arthrogryposis is space limitations in uterus, the most common etiology is oligohydramnios. The same can result from intrauterine tumours as fibroids, although to our knowledge there are only two papers reporting cases of fetal deformities related to uterine leiomyomas. We describe a well-documented exceptional case of arthrogryposis associated with the presence of a large uterine fibroid. It could illustrate the importance of a careful and appropriate assessment of uterine fibroids before and in the course of a pregnancy considering that they can cause both serious maternal and fetal complications.