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Case Reports in Obstetrics and Gynecology
Volume 2013, Article ID 189072, 5 pages
Case Report

Bilateral Ovarian Fibrothecoma Associated with Ascites, Bilateral Pleural Effusion, and Marked Elevated Serum CA-125

1Department of Gynecology and Obstetrics, University Hospital of Cocody, 01 BP V13 Abidjan, Cote D'Ivoire
2Faculty of Medicine, Félix Houphouët Boigny University of Cocody, 01 BP V 13 Abidjan, Cote D'Ivoire
3Department of Visceral and Digestive Surgery, University Hospital of Cocody, Cote D'Ivoire
4Department of Pathology, University Hospital of Treichville, Cote D'Ivoire

Received 6 November 2012; Accepted 30 December 2012

Academic Editors: S. Z. A. Badawy and M. A. Osmanagaoglu

Copyright © 2013 Védi André Serges Loué et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. The risk of ovarian cancer is increased in the association of ovarian tumor, ascites, and hydrothorax with the significant elevated tumor marker CA-125. However, this association can be observed in a rare clinical and benign pathological entity, that is Demons-Meigs’ syndrome. Objective. To describe a rare case of Demons-Meigs' syndrome observed in our department. Methods. A black African woman of 35 years old, seventh gravida and fourth parous, underwent a total abdominal hysterectomy with bilateral salpingoophorectomy for large bilateral ovarian masses associated with significant ascites, bilateral pleural effusion, and particular highly elevated tumor marker CA-125 (1835 UI/mL) in a pronounced general alteration condition. Results. The postoperative course was uneventful characterized by a complete remission of hydrothorax and ascites with normal level of CA-125 three months after tumor excision. Histology of both masses revealed a bilateral ovarian fibrothecoma, a benign tumor of the ovary, thus confirming the diagnosis of Demons-Meigs’ syndrome. Conclusion. The Demons-Meigs syndrome, although it strongly mimics the clinical picture of malignant metastatic ovarian cancer, remains a disease with benign prognosis after surgical tumor resection. This is a rare condition that must be known and recognized by practitioners to avoid unnecessary practices.