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Case Reports in Obstetrics and Gynecology
Volume 2013, Article ID 232696, 3 pages
http://dx.doi.org/10.1155/2013/232696
Case Report

Complete Androgen Insensitivity Syndrome: A Rare Case of Disorder of Sex Development

1Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Via C. Valeria 1, 98125 Messina, Italy
2Department of Gynecology and Obstetrics, Campus Bio-Medico, Via Álvaro del Portillo 200, 00128 Roma, Italy

Received 8 January 2013; Accepted 3 February 2013

Academic Editors: D. Hellberg and H.-C. Lai

Copyright © 2013 Alfonsa Pizzo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Androgen Insensitivity Syndrome (AIS) could be considered as a disease that causes resistance to androgens actions, influencing both the morphogenesis and differentiation of the body structures, and systems in which this hormone exerts its effects. It depends on an X-linked mutations in the Androgen Receptor (AR) gene that express a variety of phenotypes ranging from male infertility to completely normal female external genitalia. The clinical phenotypes of AIS could vary and be classified into three categories, as complete (CAIS), partial (PAIS), and mild (MAIS) forms, according to the severity of androgen resistance. We will describe a case of CAIS in a 16-year-old patient.