Case Report

Plasmapheresis in Acute Fatty Liver of Pregnancy: An Effective Treatment

Table 4

Comparison of similar studies.

VariablesAuthor
TangJinChuMartinCurrent study

Publication year20122012201220082012

Number of cases28 cases in two groups391163

Patient characteristics13 treatment with plasmapheresis
15 treatment with cultured liver cell
19 renal failure
14 encephalopathy
20 DIC
All cases had liver and renal failure and coagulopathy
4 ventilator dependent cases
4 encephalopathy
4 encephalopathy
3 ventilator dependent cases
5 hepatic failure
6 renal failure
First patient: hepatic and renal failure, encephalopathy, ventilator dependency and DIC
2nd patient: hepatic and renal failure, hypoglycemia and DIC
3rd patient: renal failure and coagulopathy

Time of plasmapheresis initiation after pregnancy termination6 hours later1–5 days later0–3 days later2 days laterFirst patient: 8 days
2nd patient: 6 days
3rd patient: the same day

Number of plasmapheresis sessions1–31–42–82–4 First patient: 22
2nd patient: 4
3rd patient: 3

ResultsObvious reduction in liver function recovery time, hospital stay and ICU admission duration with plasmapheresis
No difference in mortality
37 treatment
2 deaths
10 treatments
1 death
Mean ICU
Dmission day: 10 days
Mean hospital stay duration: 17 days
Complete recovery in all patients