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Case Reports in Obstetrics and Gynecology
Volume 2014, Article ID 275710, 3 pages
Case Report

Malouf Syndrome with Hypergonadotropic Hypogonadism and Cardiomyopathy: Two-Case Report and Literature Review

1Department of Obstetrics and Gynecology, Mustafa Kemal University Medical School, Hatay, Turkey
2Clinics of Obstetrics and Gynecology, Hatay Antakya Maternity Hospital, Hatay, Turkey
3Department of Genetics, Mustafa Kemal University Medical School, Hatay, Turkey
4Department of Cardiology, Mustafa Kemal University Medical School, Hatay, Turkey

Received 16 July 2014; Revised 5 November 2014; Accepted 10 November 2014; Published 3 December 2014

Academic Editor: Julio C. Rosa-e-Silva

Copyright © 2014 Dilek Benk Şilfeler et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Malouf syndrome is a very rarely encountered syndrome which was first diagnosed in 1985 upon the examination of two sisters, with findings of hypergonadotropic hypogonadism, dilated cardiomyopathy, blepharoptosis, and broad nasal base. Later on, Narahara diagnosed another sporadic case with the same findings. A survey of relevant literature leads us to three women cases in total. Here we present two cases of Malouf syndrome and literature review.