Five Cases of Non-Hodgkin B-Cell Lymphoma of the Ovary

Table 1

Details of 5 cases of ovarian NHL, presented in this report.

Patient number	Age	Presentation	Size and side	Immunophenotype	Histologic type	Ann Arbor stage	Therapy	Follow up
1	65	21 kg weight loss, night sweats, fatigue	20×15 cm left ovarian mass	CD20 (+), bcl-2 (+) pan-cytokeratin (−) S-100 (−) EMA (−) CD30 (−) HMB-45 (−) inhibin (−)	DLBCL	I BE	Sx	Developed multiorgan failure; died of disease 1 month after operation
2	61	Abdominal swelling, fatigue	20×12 cm right ovarian mass	CD20 (+) CD45 (+) bcl-2 (+) Ki-67 (+) CD3 (−)	DLBCL	I BE	Sx, CT	Died from pneumonia at the 20th postoperative month
3	53	Abdominal swelling, night sweats, frequent urination, increasing pain in the abdomen	10×8 cm right ovarian mass, 8×8 cm left ovarian mass, and 15×13 cm retroperitoneal mass in front of the aorta	CD20 (+) bcl-2 (+) pan-cytokeratin (−) S-100 (−) EMA (−) CD30 (−) CD10 (−) CD5 (−) HMB-45 (−) inhibin (−)	DLBCL	IV BE	Sx, CT, RT	6 months after surgery, alive with no evidence of recurrence
4	52	Abdominal swelling, fatigue	16×10 cm right ovarian mass	CD20 (+) bcl-2 (+); CD5 (−); CD3 (−)	DLBCL	I BE	CT	12 months after chemotherapy, alive with no evidence of recurrence
5	57	Abdominal swelling, fatigue, night sweats	16×10 cm left ovarian mass	CD20 (+) bcl-2 (+); CD5 (−); CD10 (−)	DLBCL	I BE	—	Rapidly developed multiorgan failure; died of disease in a month

DLBCL: diffuse large B-cell lymphoma; Sx: surgery; CT: chemotherapy (rituximab, cyclophosphamide, hydroxydaunorubicin, Oncovin, prednisolone (R-CHOP)); RT: radiotherapy.
F-FDG PET/CT: f-18-fluorodeoxyglucose positron emission/computerized tomography.