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Case Reports in Obstetrics and Gynecology
Volume 2015, Article ID 879538, 7 pages
http://dx.doi.org/10.1155/2015/879538
Case Report

Gestational Choriocarcinoma Presenting with Lacrimal Gland Metastasis: A First Reported Case

1Department of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia
2Gynecology Oncology Unit, Department of Obstetric and Gynecology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia
3Department of Ophthalmology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia
4Division of Neurosurgery, Faculty of Medicine, King Abdulaziz University, P.O. Box 80215, Jeddah 21589, Saudi Arabia

Received 28 January 2015; Revised 27 April 2015; Accepted 27 April 2015

Academic Editor: Cem Ficicioglu

Copyright © 2015 Naushad A. B. Ahamed et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Gestational choriocarcinoma (GC) is a recognized clinicopathological subtype of gestational trophoblastic neoplasia that usually metastasizes hematogenously to highly vascular organs like the lung, liver, and brain. However, orbital metastasis to the choroid and lacrimal gland is a rare occurrence. Case Presentation. A 21-year-old female presented with headache and left orbital swelling one year after resection of a complete hydatidiform mole followed by adjuvant methotrexate chemotherapy. A metastatic imaging screening revealed multiple metastases in the lungs, brain, and adrenal gland, in addition to the choroid and lacrimal gland. Based on her modified WHO risk factors scoring she was started on chemotherapy and whole brain radiotherapy, which resulted in a complete response. At two-year follow-up, serum b-HCG level was with normal limits; imaging surveillance was uneventful. Conclusion. We present the first case of lacrimal gland metastasis in a young girl from GC relapse.