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Case Reports in Obstetrics and Gynecology
Volume 2016, Article ID 3523760, 4 pages
Case Report

Luteoma of Pregnancy Presenting with Severe Maternal Virilisation: A Case Report

1Obstetrics and Gynecology Department, Ospedale Vittorio Emanuele-Policlinico-S. Bambino, 95123 Catania, Italy
2Obstetrics and Gynecology Department, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy

Received 4 April 2016; Accepted 9 May 2016

Academic Editor: Yoshio Yoshida

Copyright © 2016 Vincenzo Rapisarda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Luteoma of pregnancy is a rare, benign condition characterized by a tumor-like mass of the ovary that emerges during pregnancy and regresses spontaneously after delivery. It is usually asymptomatic and the diagnosis is generally incidental. Luteoma arises from the proliferation of luteinised cell under the influence of β-hCG and can be hormonally active, with production of androgens resulting in maternal and fetal hirsutism and virilisation. We report a case of a 25-year-old primigravida who presented at 28 weeks of gestation with virilisation symptoms. Serum androgen levels were seven-hundred-fold higher than normal. A diagnosis of pregnancy luteoma was made at the time of caesarean section. The ovarian mass, serum androgen levels, and the condition of the patient improved after delivery.