Case Reports in Obstetrics and Gynecology / 2016 / Article / Tab 1

Case Report

A Case of New-Onset Dermatomyositis in the Second Trimester of Pregnancy: A Case Report and Review of the Literature

Table 1

Dermatomyositis complicating pregnancy. Review of the cases.

Author [ref.]PatientAge at diagnosis (years)DM onsetDisease activity (during pregnancy)TreatmentFetal outcome

Glickman [7]127BPImprovedPrednisoneHealthy

Masse [8]126BPImprovedACTHHealthy
InactiveACTHAbortion

Tsai et al. [9]133DPActiveNo treatmentNeonatal death

Gutierrez et al. [6] 1NIDPActivePrednisoneAbortion
2NIDPActivePrednisoneStillbirth
3JDMBPInactiveNo treatmentAbortion
ExacerbationPrednisonePremature
4NIPPInactiveNo treatmentAbortion
InactiveNo treatmentCaesarean at term
5NIBPInactiveNo treatmentHealthy
6NIBPExacerbationPrednisonePremature
InactiveNo treatmentTwins Premature/neonatal death

King and Chow [10] 112BPInactiveNo treatmentIUGR
InactiveNo treatmentHealthy
220BPInactiveNo treatmentHealthy
InactiveNo treatmentHealthy
325BPExacerbationPrednisoneHealthy

England et al. [11]135DPActiveSteroidIUGR

Ishii et al. [12] 131DPActiveSteroidHealthy
InactiveSteroidHealthy

Pinheiro Gda et al. [2]114DPActiveSteroidHealthy

Suwa et al. [13]129PPSpontaneous remission

Harris et al. [14]129DPActiveInduced labor, pulse steroid PPHealthy

Solomon and D’Alton [15]128DPActiveSteroidHealthy

Kofteridis et al. [16]125DPActivePulse steroidAbortion

Kanoh et al. [17]133PPPrednisolone PP

Lee and Yoo [18]133PPMethylprednisolone PP

Silva et al. [4] 122BPActive, no changeSteroid, MTXAbortion
228BPInactivePrednisoloneHealthy

Park et al. [19]122DPActiveTherapeutic abortion, IVIG PPAbortion

Mosca et al. [20]132DPActiveMethylprednisolone, IVIGHealthy

Pasrija et al. [21]127DPActiveDexamethasone, HCQHealthy

Váncsa et al. [22] 122BPInactiveMethylprednisoloneHealthy
InactiveMethylprednisoloneAbortion
228BPInactiveMethylprednisoloneHealthy
333BPInactiveNo treatmentHealthy
437DPActiveMethylprednisolonePremature
530BPInactiveNo treatmentHealthy

Chopra et al. [23] 128BPInactiveNo treatmentHealthy
InactiveNo treatmentIUGR

Nozaki et al. [24]131DPActivePrednisolone, IVIG PPPremature

Linardaki et al. [25]142DPActiveMethylprednisolone, IVIGHealthy

Madu et al. [26]1JDMBPExacerbationPrednisoloneHealthy

Pinal-Fernandez et al. [3] 135BPImprovementPrednisone, MTXInduced abortion
ImprovementPrednisoneHealthy
ImprovementPrednisoneHealthy
235BPImprovementPrednisoneHealthy
ImprovementPrednisoneHealthy
338BPImprovementPrednisoneInduced abortion (anencephaly)
ImprovementPrednisoneHealthy
ImprovementPrednisoneHealthy
432PPPrednisone PP
531BPAsymptomaticNo treatmentHealthy
AsymptomaticNo treatmentAbortion
636BPNo changePrednisoneHealthy

Present case140DPActiveMethylprednisolonePremature

BP, before pregnancy; DP, during pregnancy; PP, puerperal period; NI, not indicated; JDM, juvenile dermatomyositis; ACTH, adrenocorticotrophic hormone; IVIG, intravenous immunoglobulin; MTX, methotrexate; HCQ, hydroxychloroquine; IUGR, intrauterine growth restriction.

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