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Case Reports in Obstetrics and Gynecology
Volume 2017, Article ID 2947927, 4 pages
Case Report

Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval

1Department of Obstetrics and Gynecology, Sakai City Medical Center, Sakai, Japan
2Department of Pathology, Sakai City Medical Center, Sakai, Japan

Correspondence should be addressed to Toshiya Yamamoto; pj.latipsoh-iakas@ot-otomamay

Received 12 January 2017; Revised 2 April 2017; Accepted 16 April 2017; Published 21 May 2017

Academic Editor: Hans Rudolf Tinneberg

Copyright © 2017 Mariko Jitsumori et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 67-year-old uniparous woman had undergone surgery for acute perforated gastric ulcer 10 years prior to the current presentation. Although abdominal computed tomography (CT) performed at that point had revealed a mature cystic teratoma measuring 6 cm in diameter in the right ovary, it was left untreated. She visited the department of surgery at our hospital with chief complaints of appetite loss, nausea, and vomiting that had persisted for the prior two weeks. She was admitted with a diagnosis of ileus attributed to an abdominal incisional hernia. CT performed on admission revealed a tumor measuring 21 cm in diameter with mural nodules in the right ovary. Thus, surgery was performed under suspicion of malignant transformation of the previously detected ovarian mature cystic teratoma. While neither lymphadenopathy nor distant metastasis was detected by imaging studies, bilateral adnexectomy and repair of the abdominal incisional hernia were performed. Cytology of ascites was negative. The postoperative pathological diagnosis was squamous cell carcinoma arising from teratoma, and the postoperative clinical diagnosis was stage IA ovarian cancer. It was assumed that the mature cystic teratoma which had been detected in the right ovary 10 years earlier had undergone malignant transformation.