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Case Reports in Obstetrics and Gynecology
Volume 2018, Article ID 5643040, 3 pages
Case Report

Malignant Transformation of Endometriosis in the Ischioanal Fossa

1Department of Obstetrics & Gynecology, Christiana Care Health System, Newark, DE, USA
2Division of Gynecologic Oncology, Christiana Care Health System, Newark, DE, USA

Correspondence should be addressed to Jordan S. Klebanoff; gro.eracanaitsirhc@ffonabelkj

Received 7 January 2018; Accepted 19 March 2018; Published 23 April 2018

Academic Editor: Seung-Yup Ku

Copyright © 2018 Jordan S. Klebanoff et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present the case of a 28-year-old nulliparous female with malignant transformation of an ectopic focus of endometriosis in the right ischioanal fossa. A 28-year-old nulliparous patient with a past medical history of polycystic ovarian syndrome (PCOS) was diagnosed with endometrioid adenocarcinoma in her right ischioanal fossa. Initially, patient presented to an emergency department and underwent a CT scan of the appendix to rule out appendicitis. A multiloculated cystic lesion adjacent to the right obturator internus muscle was found. She underwent surgical resection of the mass, which confirmed FIGO grade 2 endometrioid adenocarcinoma, followed by localized radiation therapy. Malignancy arising in endometriosis is rare, and the influence of PCOS on the rate of malignant transformation is not well established.