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Case Reports in Obstetrics and Gynecology
Volume 2018, Article ID 6073204, 7 pages
https://doi.org/10.1155/2018/6073204
Case Report

Ultrasound Presentation of a Disseminated Fetal and Neonatal Rhabdoid Tumor

1Department of Obstetrics and Gynaecology, CHU de Rennes, Hospital Anne de Bretagne, 16 Bd de Bulgarie, BP 90347, 35 203 Rennes Cedex 2, France
2Department of Radiology, CHU de Rennes, Hospital Anne de Bretagne, 16 Bd de Bulgarie, BP 90347, 35 203 Rennes Cedex 2, France
3Department of Pathology, CHU de Rennes, Hospital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
4Department of Pathology, Leon Berard Center, 28 rue Laennec, 69008 Lyon, France
5Department of Genetics, CHU de Rennes, Hospital Anne de Bretagne, 16 Bd de Bulgarie, BP 90347, 35 203 Rennes Cedex 2, France
6Medical School, University of Rennes 1, 2 Avenue du Professeur Léon Bernard, 35000 Rennes, France
7Institut Curie, Paris Sciences et Lettres Research University, Inserm U830, Laboratoire de Genetique et Biologie des Cancers, 26 rue d’Ulm, 75005 Paris, France

Correspondence should be addressed to Yolaine Joueidi; rf.egnaro@idieuoj.enialoy

Received 2 December 2017; Accepted 8 January 2018; Published 31 January 2018

Academic Editor: Erich Cosmi

Copyright © 2018 Yolaine Joueidi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This is a case report of a disseminated fetal rhabdoid tumor discovered at 32 weeks of gestation in a 29-year-old woman on immunosuppressive therapy. The mother consulted for a decrease in fetal movement. Fetal ultrasound showed signs of a disseminated tumor affecting the left armpit, liver, spleen, and limbs. A caesarian section was performed because of signs of fetal distress. Immunohistochemical analysis of a fetal biopsy showed deletion of the SMARCB1 gene. Pathological analysis of the placenta showed a rhabdoid tumor invading both fetal and maternal compartments. The mother underwent a whole-body MRI, and no metastasis was found. To the best of our knowledge, this is the first report of a disseminated rhabdoid tumor invading both fetal and maternal compartments.