Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review

Table 1

Summary of the uterine epithelioid angiosarcomas in literature review. TAH: total abdominal hysterectomy, BSO: bilateral salpingo-oophorectomy, LSO: left salpingo-oophorectomy, RSO: right salpingo-oophorectomy, POM: partial omentectomy, PLN: pelvic lymphadenectomy, PAN: para-aortic lymphadenectomy, NED: no evidence of disease, DOD: dead of disease.

Case No.	Author (Year)	Age	size	Presentation	Treatment	Outcome (months)
1	Purola and Strandell (1967)	57	−	Vaginal bleeding	TAH, BSO appendectomy, RT	NED, 18mo
2	Ehrmann and Griffiths (1979)	17	9	Vaginal bleeding	TAH, LSO, CT, RT	DOD, 84mo
3	Ongkasuwan (1982)	70	11	Malaise weight loss	TAH, BSO	NED, 5mo
4	Witkin (1987)	71	15×17×7	Vaginal bleeding	TAH, BSO, RT	Reccurence 6mo
5	Milne (1990)	76	18	Vaginal bleeding urinary retention	TAH, BSO	DOD, 6mo
6	Quinonez (1991)	65	8	Vaginal bleeding	TAH, BSO, PLN; CT, RT	NED, 48mo
7	Lack (1991)	71	−	Vaginal bleeding	TAH, BSO, RT	DOD, 2mo
8	Tallini (1993)	56	30×24	Vaginal bleeding	TAH, BSO, POM PAN, appendectomy,	DOD, 7mo
9	Drachenberg (1994)	58	12	Vaginal bleeding	TAH, BSO, CT, RT	DOD, 2mo
10	Schammel (1998)	49	29×29×19	Vaginal mass	TAH, BSO	DOD, 3mo
11	Schammel (1998)	58	12	Vaginal bleeding	TAH, BSO, CT, RT	DOD, 2mo
12	Schammel (1998)	70	5×3×3	Vaginal bleeding	TAH, BSO	NED, 37mo
13	Schammel (1998)	75	6×6×5	Vaginal bleeding	TAH, BSO	DOD, 7mo
14	Mendez (1999)	59	12-wk-size uterus	Vaginal bleeding	TAH, BSO	DOD, 2.5mo
15	Konishi (2007)	62	17×15×7.5	Anemia	TAH, BSO, CT	NED, 2mo
16	Cardinale (2008)	81	8×7×5	Lower abdominal pain anemia	TAH, BSO	DOD, 6mo
17	Cardinale (2008)	35	25	Shortness of breath dry cough	TAH, BSO	No information
18	Olawaiye (2008)	54	11×6	Enlarged uterus	TAH, BSO	NED,12mo
19	Hwang and Lim (2013)	61	12×10×9	Vaginal bleeding	TAH, BSO, PAN, RT	No information
20	Suzuki (2014)	64	7.5×5.5×3.5	Vaginal bleeding	TAH, BSO	DOD, 50mo
21	Yankun Liu (2015)	56	11×8×7	Anemia	TAH, BSO	No information
22	Strickland (2017)	67	21×18×15	Fatigue, weight loss	TAH, BSO	DOD, 2mo