A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman

Figure 3

The specimen showed the left ovarian tumour and fallopian tube of the patient. The gross specimen consisted of a lobulated mass 100 x 100 x 30 mm with a defect measuring 20 mm in size externally, altogether weighing 177 grams. The mass had morcellated appearance. On cut section had solid and multicystic appearance. The solid areas had a golden yellow appearance punctuated by foci of haemorrhage. A small fleshy tan solid-cystic area was present at one end measuring 20 x 15 x 15 mm. In cytological examination, the sections of the main tumour showed a predominantly diffuse proliferation of polygonal cells with ample, pale, vacuolated cytoplasm and round central nuclei. Small areas of a more nested appearance were also seen. Foci showing cells with more eosinophilic cytoplasm were also evident, but no Reinke crystals were evident. The nuclei were central and round, with no significant atypia. Immunohistochemical stains for calretinin and alpha-inhibin were diffusely and strongly positive. CD 10 is negative. An area showing multiple cystic structures lined by bland cuboidal to columnar epithelium with focal ciliation in a fibromatous stroma was seen. No significant epithelial proliferation or atypia was seen.