Fatal Postpartum Hemorrhage in Diffuse Midline Glioma with H3-K27M Mutation

Figure 2

Hematoxylin-Eosin (H&E) staining revealed proliferation of various palisading cells with bipolar nature and no obvious findings of Rosenthal fiber (A, B). The immunohistochemical status of IDH1 showed wildtype IDH1 (C) and the Ki-67 labeling index was approximately 4% (D). CD34 staining suggested low microvascular proliferation (E). The optical magnification ratio of photomicrographs is 200-fold except for (B) (400-fold). The histone H3-K27M mutation was detected by Sanger sequencing (F).