Use of Ceftolozane/Tazobactam in a Case of Septic Shock by Puerperal Sepsis

Table 1

Main clinical events during ICU hospitalization.

DAY OF HOSPITALIZATION IN ICU	MAIN CLINICAL EVENTS
1	ICU Admission; start infusion of norepinephrine
2
3	Patient’s blood culture test positive for Escherichia coli
4	Start of invasive mechanical ventilation; thoracic drainage
5	Severe neutropenia (WBC: 0,740 cells/mm^3)
6	Dehiscence of the surgical wound
7	Bronchoalveolar lavage (positivity for Acinetobacter baumannii)
8
9	Stop infusion of norepinephrine
10	Respiratory weaning and extubation
11
12	Diagnosis of motor polyneuropathy
13
14
15	Respiratory failure; restart of invasive mechanical ventilation
16	Hypotension with restore of norepinephrine infusion
17	Severe thrombocytopenia treated with transfusion
18	Diagnosis of multiple abdominal abscesses
19	Start therapy with ceftolozane/tazobactam
20	Exploratory laparotomy with abscesses drainage
21
22	Respiratory weaning with extubation; stop norepinephrine infusion
23
24
25	ICU Discharge